COLM papers

Advanced CLARITY for rapid and high-resolution imaging of intact tissues. Tomer R, Ye L, Hsueh B, and K Deisseroth. Nature Protocols 9(7):1682–1697.

High-resolution figures

Figure 1: CLARITY pipeline overview
Figure 2: ETC
Figure 3: Imaging clarified samples
Figure 4: COLM
Figure 5: Ultrafast imaging of whole mouse brain using COLM
Figure 6: Fast high-resolution imaging of clarified brain using COLM
Figure 7: Optimized confocal microscopy of clarified samples
Figure 8: Molecular interrogation of clarified tissue

Supplementary Figure 1: Sample transparency at key stages of the CLARITY protocol
Supplementary Figure 2: Summary of the control electronics framework and COLM parts

High-resolution videos

Supplementary Video 1
Supplementary Video 2
Supplementary Video 3